Corpus ID: 7973042

Morphometric analysis of Bruch's membrane, the choriocapillaris, and the choroid in aging.

  title={Morphometric analysis of Bruch's membrane, the choriocapillaris, and the choroid in aging.},
  author={R. S. Ramrattan and T. L. van der Schaft and C. Mooy and W. D. de Bruijn and P. Mulder and P. T. D. de Jong},
  journal={Investigative ophthalmology & visual science},
  volume={35 6},
  • R. S. Ramrattan, T. L. van der Schaft, +3 authors P. T. D. de Jong
  • Published 1994
  • Chemistry, Medicine, Computer Science
  • Investigative ophthalmology & visual science
  • PURPOSE To quantify changes in choriocapillary density and in thickness of Bruch's membrane, the choriocapillaris, and the choroid in 95 unpaired, histologically normal human maculae aged 6 to 100 years and in 25 maculae with advanced age-related macular degeneration. METHODS Light microscopic, computer-aided, morphometric quantitative analysis. RESULTS In ten decades, Bruch's membrane thickness increased by 135%, from 2.0 to 4.7 microns; the choriocapillary density decreased by 45%; the… CONTINUE READING
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