Corpus ID: 7973042

Morphometric analysis of Bruch's membrane, the choriocapillaris, and the choroid in aging.

@article{Ramrattan1994MorphometricAO,
  title={Morphometric analysis of Bruch's membrane, the choriocapillaris, and the choroid in aging.},
  author={R. S. Ramrattan and T. L. van der Schaft and C. Mooy and W. D. de Bruijn and P. Mulder and P. T. D. de Jong},
  journal={Investigative ophthalmology & visual science},
  year={1994},
  volume={35 6},
  pages={
          2857-64
        }
}
  • R. S. Ramrattan, T. L. van der Schaft, +3 authors P. T. D. de Jong
  • Published 1994
  • Chemistry, Medicine, Computer Science
  • Investigative ophthalmology & visual science
  • PURPOSE To quantify changes in choriocapillary density and in thickness of Bruch's membrane, the choriocapillaris, and the choroid in 95 unpaired, histologically normal human maculae aged 6 to 100 years and in 25 maculae with advanced age-related macular degeneration. METHODS Light microscopic, computer-aided, morphometric quantitative analysis. RESULTS In ten decades, Bruch's membrane thickness increased by 135%, from 2.0 to 4.7 microns; the choriocapillary density decreased by 45%; the… CONTINUE READING
    621 Citations
    Age-Related Changes in the Chorioretinal Junction: An Immunohistochemical Study
    • 4
    Morphometric analysis of the choroid, Bruch's membrane, and retinal pigment epithelium in eyes with age-related macular degeneration.
    • 186
    • PDF
    Relationship between RPE and choriocapillaris in age-related macular degeneration.
    • 360
    • Highly Influenced
    • PDF
    Choroidal changes associated with Bruch membrane pathology in pseudoxanthoma elasticum.
    • 18
    The Aging of the Choroid
    • 2
    Bruch's membrane and choroidal macrophages in early and advanced age-related macular degeneration
    • 175
    Accumulation of cholesterol with age in human Bruch's membrane.
    • 389
    • PDF
    Choriocapillaris Degeneration in Geographic Atrophy.
    • 14

    References

    SHOWING 1-10 OF 31 REFERENCES
    A histologic study of regional choroidal dystrophy.
    • 29
    Is basal laminar deposit unique for age-related macular degeneration?
    • 63
    Does the retinal pigment epithelium polarize the choriocapillaris?
    • 49
    Ageing and degeneration in the macular region: a clinico-pathological study.
    • S. Sarks
    • Medicine
    • The British journal of ophthalmology
    • 1976
    • 730
    • PDF
    RPE destruction causes choriocapillary atrophy.
    • 356
    • PDF
    Pathologic Features of Senile Macular Degeneration
    • 368
    Senile choroidal vascular patterns and drusen.
    • 153
    Macrophages related to Bruch's membrane in age-related macular degeneration
    • 264
    • PDF