Morphology of the airway wall in asthma and in chronic obstructive pulmonary disease.

@article{Jeffery1991MorphologyOT,
  title={Morphology of the airway wall in asthma and in chronic obstructive pulmonary disease.},
  author={Peter K. Jeffery},
  journal={The American review of respiratory disease},
  year={1991},
  volume={143 5 Pt 1},
  pages={1152-8; discussion 1161}
}
Asthma and chronic obstructive pulmonary disease (COPD) are complex conditions with imprecise definitions, which make definitive morphologic comparisons difficult. Broadly, the airways in asthma are occluded by tenacious plugs of exudate and mucus, and there is fragility of airway surface epithelium, thickening of the reticular layer beneath the epithelial basal lamina, and bronchial vessel congestion and edema. There is increased inflammatory infiltrate comprising "activated" lymphocytes and… CONTINUE READING

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