Morphology of perineuronal nets in tenascin-R and parvalbumin single and double knockout mice.

@article{Hauns2000MorphologyOP,
  title={Morphology of perineuronal nets in tenascin-R and parvalbumin single and double knockout mice.},
  author={A Hauns\o and Merdol Ibrahim and Udo Bartsch and Maryse Letiembre and Marco R. Celio and P A Menoud},
  journal={Brain research},
  year={2000},
  volume={864 1},
  pages={142-5}
}
Recently identified chondroitin sulphate proteoglycans in perineuronal nets include neurocan and phosphacan. However, the function and assembly of these components has yet to be resolved. In this study we show morphological alteration in Wisteria floribunda labelled nets around cortical interneurones both in tenascin-R knockout and tenascin-R/parvalbumin double knockout mice. This alteration reflects the loss of phosphacan and neurocan from cortical nets in mice deficient in tenascin-R. No… CONTINUE READING