Morphology of nanostructures and their long-acting properties in vivo for a novel synthetic peptide of gonadotropin-releasing hormone antagonist.

Abstract

OBJECTIVES To demonstrate the correlation between the nanostructure formation and the long duration of action in vivo of peptides, the morphology of nanostructures of LXT-101, a novel synthetic amphiphilic peptide of gonadotropin-releasing hormone antagonist were observed when dissolved in different solvents, and their long-acting properties in vivo were… (More)
DOI: 10.1111/jphp.12233

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