Morphology of hepatitis C and hepatitis B virus particles as detected by immunogold electron microscopy

  title={Morphology of hepatitis C and hepatitis B virus particles as detected by immunogold electron microscopy},
  author={M. Kaito and Satoshi Ishida and H. Tanaka and S. Horiike and N. Fujita and Y. Adachi and M. Kohara and Masayoshi Konishi and S. Watanabe},
  journal={Medical Molecular Morphology},
  • M. Kaito, Satoshi Ishida, +6 authors S. Watanabe
  • Published 2006
  • Biology, Medicine
  • Medical Molecular Morphology
  • We performed indirect immunogold electron microscopy (EM) for immunological identification and characterization of hepatitis C virus (HCV). To clarify the morphology of HCV, an indirect immunogold EM of two plasma samples from patients with high HCV RNA titers was carried out using antibodies specific for the putative HCV envelope protein (E) 1. Spherical virus particles 55–65 nm in diameter with delicate spike projections were detected in the 1.14–1.16 g/ml fractions after sucrose density… CONTINUE READING
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