Morphology of experimental antibiotic-associated enterocolitis in the hamster: a model for human pseudomembranous colitis and antibiotic-associated diarrhoea.

@article{Price1979MorphologyOE,
  title={Morphology of experimental antibiotic-associated enterocolitis in the hamster: a model for human pseudomembranous colitis and antibiotic-associated diarrhoea.},
  author={Ashley B Price and H. T. Larson and J. Crow},
  journal={Gut},
  year={1979},
  volume={20 6},
  pages={467-75}
}
The morphology of antibiotic-associated enterocolitis in the hamster is described and compared with human antibiotic-associated pseudomembranous colitis. It is shown to be a caecal disease with proliferative mucosal changes and in this respect unlike the human counterpart. The bacteriology and toxicology, however, are identical. In addition, mucosal changes are described in animals on antibiotics but without established enterocolitis. As a result we suggest that there may be a spectrum of human… CONTINUE READING

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Neutral - ization by Clostridium sordellii antitoxin of toxins implicated in clindamycin - induced cecitis in the hamster

  • G. D. Rifkin, F. R. Fekety, J. Silva
  • Lancet
  • 1978
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