Morphology of dentate granule cells in the human epileptogenic hippocampus.

  title={Morphology of dentate granule cells in the human epileptogenic hippocampus.},
  author={G von Campe and Dennis D. Spencer and Nihal C. de Lanerolle},
  volume={7 5},
Hippocampal dentate granule cells in temporal lobe epilepsy (TLE) patients with mesial sclerosis (MTLE) are reported to be hyperexcitable compared to those in patients with a mass lesion outside the hippocampus (MaTLE) (Williamson, Clin Neurosci 1994;2: 47-52). To determine if such hyperexcitability is associated with an altered morphology of these neurons, Lucifer Yellow-filled granule cells from MTLE patients were compared with those from MaTLE. The morphology of granule cells in both subject… CONTINUE READING

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