Morphology and transfection study of human microvascular endothelial cell angiogenesis: an in vitro three-dimensional model.

Abstract

Microvascular endothelial cells from human neonatal foreskin were grown in vitro until a three-dimensional network of capillary-like structures was formed. All stages of the angiogenic cascade could be observed in this in vitro model, including the formation of an internal lumen. The microscopy focused on morphology, formation of an internal lumen, role of… (More)

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