Morphology and myofiber composition of skeletal musculature of the forelimb in young and aged wild type and myostatin null mice.

@article{Elashry2009MorphologyAM,
  title={Morphology and myofiber composition of skeletal musculature of the forelimb in young and aged wild type and myostatin null mice.},
  author={Mohamed I. Elashry and Anthony Otto and Antonios Matsakas and Salah E El-Morsy and Ketan Patel},
  journal={Rejuvenation research},
  year={2009},
  volume={12 4},
  pages={
          269-81
        }
}
Most current research into therapeutic approaches to muscle diseases involves the use of the mouse as an experimental model. Furthermore, a major strategy to alleviate myopathic symptoms through enhancing muscle growth and regeneration is to inhibit the action of myostatin (Mstn), a transforming growth factor-beta (TGF-beta) family member that inhibits muscle growth. Presently, however, no study has expanded the morphological analysis of mouse skeletal muscle beyond a few individual muscles of… CONTINUE READING

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