Morphologists overestimate the nuclear-to-cytoplasmic ratio.

  title={Morphologists overestimate the nuclear-to-cytoplasmic ratio.},
  author={Mingjuan Lisa Zhang and Alan Xinyu Guo and Christopher J VandenBussche},
  journal={Cancer cytopathology},
  volume={124 9},
BACKGROUND The Paris System for Reporting Urinary Cytology (TPS) has defined nuclear-to-cytoplasmic (N:C) ratio cutoff values for several of its risk-stratified diagnostic categories. However, because pathologists are not trained to recognize strict N:C ratio cutoff values, a previously designed survey was used to determine whether pathologists could accurately identify N:C ratios according to TPS standards. METHODS Participants were instructed to estimate the N:C ratio of ideal (line drawing… CONTINUE READING

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