Morphologically Constrained and Data Informed Cell Segmentation of Budding Yeast

  title={Morphologically Constrained and Data Informed Cell Segmentation of Budding Yeast},
  author={Elco Bakker and Peter S. Swain and Matthew M. Crane},
Motivation Although high-content image cytometry is becoming increasingly routine, processing the large amount of data acquired during time-lapse experiments remains a challenge. The majority of approaches for automated single-cell segmentation focus on flat, uniform fields of view covered with a single layer of cells. In the increasingly popular microfluidic devices that trap individual cells for long term imaging, these conditions are not met. Consequently, most segmentation techniques… 

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    Cytometry. Part A : the journal of the International Society for Analytical Cytology
  • 2020
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