Morphological spectrum of polyoma virus disease in renal allografts: diagnostic accuracy of urine cytology.

@article{Drachenberg2001MorphologicalSO,
  title={Morphological spectrum of polyoma virus disease in renal allografts: diagnostic accuracy of urine cytology.},
  author={Rene C Drachenberg and Cinthia B Drachenberg and John C. Papadimitriou and Emilio Luis Lucio-Villegas Ramos and Jeffrey C. Fink and Ravinder Wali and MatthewR. Weir and Charles B. Cangro and David K Klassen and Amr Khaled and Ronan G C Cunningham and Stephen T. Bartlett},
  journal={American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons},
  year={2001},
  volume={1 4},
  pages={
          373-81
        }
}
The morphological features of polyoma virus disease (PVDz) in 571 concurrent urine and biopsy samples from 413 patients are described. In 54 patients PV was found in both biopsy and urine samples. Histologically, PV presented as: (a) mild, viral cytopathic/cytolytic changes, with absent or minimal inflammation involving isolated tubules; (b) moderate and severe, cytopathic/cytolytic changes associated with patchy or diffuse tubulo-interstitial inflammation and atrophy; (c) advanced, graft… CONTINUE READING
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