Morphological relationships between peptidergic nerve fibers and immunoglobulin A-producing lymphocytes in the mouse intestine.

@article{Shibata2008MorphologicalRB,
  title={Morphological relationships between peptidergic nerve fibers and immunoglobulin A-producing lymphocytes in the mouse intestine.},
  author={Maiko Shibata and Tatsuya Hisajima and Masato Nakano and Richard C. Goris and Kengo Funakoshi},
  journal={Brain, behavior, and immunity},
  year={2008},
  volume={22 2},
  pages={158-66}
}
Immunoglobulin A (IgA) lymphocytes are present close to the nerve fibers in the lamina propria of the small intestine, and the administration of lipopolysaccharides (LPSs) increases the number of these cells and IgA secretion to the lumen. In the present study, we demonstrated that the nerve fibers immunoreactive for vasoactive intestinal peptide (VIP), neuropeptide Y (NPY), and calcitonin gene-related peptide (CGRP) were close to the IgA lymphocytes in the mouse ileum lamina propria. Three… CONTINUE READING