Morphological impairments in retinal neurons of the scotopic visual pathway in a monkey model of Parkinson's disease.

@article{Cuenca2005MorphologicalII,
  title={Morphological impairments in retinal neurons of the scotopic visual pathway in a monkey model of Parkinson's disease.},
  author={Nicol{\'a}s Cuenca and M. Esther Llorente Herrero and Antonia Angulo and Emilio de Juan and Gema C. Mart{\'i}nez-Navarrete and Salvador Guerrero L{\'o}pez and Carlos Barcia and Jos{\'e} Mart{\'i}n-Nieto},
  journal={The Journal of comparative neurology},
  year={2005},
  volume={493 2},
  pages={
          261-73
        }
}
Physiological abnormalities resulting from death of dopaminergic neurons of the central nervous system in Parkinson's disease also extend to the retina, resulting in impaired visual functions. In both parkinsonian patients and animal models, low levels of dopamine and loss of dopaminergic cells in the retina have been reported. However, the morphology and connectivity of their postsynaptic neurons, the amacrine cells, have not been analyzed. Here we report, with macaques chronically treated… CONTINUE READING
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