Morphological evidence for the ability of eosinophils to damage antibody-coated schistosomula.


Schistosomula of Schistosoma mansoni were incubated with preparations from human peripheral blood containing up to 98% eosinophils, in the presence or absence of anti-schistosomular antibody. It was found that there was a correlation between damage to the schistosomula, as judged by phase-contrast microscopy, and release of 51chromium from labelled… (More)