Morphological differences in Parkinson’s disease with and without rest tremor

@article{Benninger2009MorphologicalDI,
  title={Morphological differences in Parkinson’s disease with and without rest tremor},
  author={D H Benninger and MSc S. Thees and Spyridon S. Kollias and Claudio Bassetti and Daniel Waldvogel},
  journal={Journal of Neurology},
  year={2009},
  volume={256},
  pages={256-263}
}
Rest tremor is a hallmark of Parkinson’s disease (PD), but its pathogenesis remains incompletely understood. Nigro-striatal dopamine deficiency correlates best with bradykinesia, but not with tremor. Oscillating neurons in one or multiple localizations within the basal gangliathalamo-cortical loop may cause rest tremor, and an active contribution of the cerebellum and the cerebello-thalamo-cortical projections has been postulated. To compare the pattern of grey matter volume in PD patients with… CONTINUE READING

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