Morphological differences between projection neurons of the core and shell in the nucleus accumbens of the rat

@article{Meredith1992MorphologicalDB,
  title={Morphological differences between projection neurons of the core and shell in the nucleus accumbens of the rat},
  author={Gloria E. Meredith and R. Agolia and Monique P. M. Arts and Henk J. Groenewegen and Daniel S Zahm},
  journal={Neuroscience},
  year={1992},
  volume={50},
  pages={149-162}
}
The somatodendritic morphology of projection neurons in the shell and core of the rat nucleus accumbens was studied. These cells were retrogradely labelled with Fast Blue from the ventral mesencephalon (substantia nigra/ventral tegmental area) and subsequently injected intracellularly with Lucifer Yellow and processed immunocytochemically. Digitized reconstructions revealed that the cell bodies of neurons located throughout the nucleus are small-to-medium in size. Neurons in the shell have… Expand
Differences in the laminar origin of projections from the medial prefrontal cortex to the nucleus accumbens shell and core regions in the rat
TLDR
The retrogradely transported Neurobiotin was found in somata, proximal and distal dendrites of neurons that project from the mPFC to the nucleus accumbens and confirmed that the projection arises wholly from pyramidal cells. Expand
Immunohistochemical Characterization of the Shell and Core Territories of the Nucleus Accumbens in the Rat
The nucleus accumbens in the rat has been parcelled into shell and core subdivisions. Despite accumulating evidence for such a division of the nucleus accumbens, these territories have not beenExpand
An electron microscopic morphometric comparison of tyrosine hydroxylase immunoreactive innervation in the neostriatum and the nucleus accumbens core and shell
TLDR
It is probably that the effects of the dopaminergic innervation in the core resemble the effects in neostriatum more than do those in the shell, and the core of the nucleus accumbens is aligned with neostariatum and the shell is different from the core and neostRIatum. Expand
Relationships of the Dendritic Arborizations of Ventral Striatomesencephalic Projection Neurons With Boundaries of Striatal Compartments. An In Vitro Intracellular Labelling Study in the Rat
TLDR
The present results demonstrate that the dendrites of the great majority of ventral striatomesencephalic neurons comply with the boundaries of Ventral striatal enkephalin compartments, and suggest the existence of discrete channels through the ventral mesencephalon. Expand
Possible pathways through which neurons of the shell of the nucleus accumbens influence the outflow of the core of the nucleus accumbens
TLDR
The aim of this study was to identify pathways of the efferents of the shell of the Acb to influence the outflow of the core of theAcb in chloral hydrate-anesthetized male Sprague-Dawley rats. Expand
The structural basis for mapping behavior onto the ventral striatum and its subdivisions
TLDR
This review is focused on evaluating the structural differences in nucleus accumbens core and shell neurons and discusses how such different morphologies could underlie distinguishable behavioral processes. Expand
Topographical organization of projections from the entorhinal cortex to the striatum of the rat
TLDR
The present observations that entorhinal inputs to the nucleus accumbens are regionally aligned suggest that disruption of these connections could produce site-specific deficits with, presumably, specific behavioural consequences. Expand
Specificity in the efferent projections of the nucleus accumbens in the rat: Comparison of the rostral pole projection patterns with those of the core and shell
TLDR
The efferent connections of the rostral pole of the rat accumbens were examined with the aid of the anterogradely transported plant lectin, Phaseolus vulgaris‐leucoagglutinin (PHA‐L), for comparison with the previously reported projection patterns of the accumbal core and shell, provoking the speculation that ventral striatal calbindin immunoreactive cells contribute principally to basal ganglia‐like projections. Expand
Effects of dopamine depletion on the morphology of medium spiny neurons in the shell and core of the rat nucleus accumbens
TLDR
Data suggest that the loss of dopamine can affect accumbal neuronal morphology and, moreover, can affect neuronal structures differentially in the shell and core of animals that received a unilateral, chronic 6- hydroxydopamine lesion of the medial forebrain bundle. Expand
Evidence for a multi‐compartmental histochemical organization of the nucleus accumbens in the rat
TLDR
A comparison of the connectivity patterns and neurochemical characteristics of the opioid receptor‐dense compartments in the nucleus accumbens with those in the caudate‐putamen reveals major discrepancies between these two striatal subdivisions. Expand
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 69 REFERENCES
Relationships of the Dendritic Arborizations of Ventral Striatomesencephalic Projection Neurons With Boundaries of Striatal Compartments. An In Vitro Intracellular Labelling Study in the Rat
TLDR
The present results demonstrate that the dendrites of the great majority of ventral striatomesencephalic neurons comply with the boundaries of Ventral striatal enkephalin compartments, and suggest the existence of discrete channels through the ventral mesencephalon. Expand
Specificity in the projection patterns of accumbal core and shell in the rat
The efferent projections of the core and shell areas of the nucleus accumbens were studied with a combination of anterograde and retrograde tract-tracing methods, including PhaseolusExpand
Compartmental distribution of ventral striatal neurons projecting to the mesencephalon in the rat
TLDR
The present results imply that through the ventral striatal compartments information from disparate combinations of cortical and thalamic sources may be conveyed to distinct mesencephalic targets. Expand
The distribution and compartmental organization of the cholinergic neurons in nucleus accumbens of the rat
TLDR
The findings show that the cholinergic elements are differentially distributed within nucleus accumbens; that these elements are compartmentally ordered; and that, in light of their limited access to other compartments, they possibly play only a minor role in intercompartmental communication. Expand
Cell clusters in the nucleus accumbens of the rat, and the mosaic relationship of opiate receptors, acetylcholinesterase and subcortical afferent terminations
TLDR
Findings suggest that the cell clusters are way-stations devoted to intrinsic information processing in the nucleus accumbens and can be extended to chemically similar arrangements in the caudate-putamen, which lacks a cytoarchitectural unit as distinct as the cell cluster. Expand
Compartmental organization of the ventral striatum of the rat: Immunohistochemical distribution of enkephalin, substance P, dopamine, and calcium‐binding protein
TLDR
In the caudate‐putamen of the rat a patch/matrix organization can be recognized on the basis of the immunohistochemical distribution of several markers, which include enkephalin, substance P, dopamine, and calcium‐binding protein, which were investigated in the nucleus accumbens. Expand
Two transpallidal pathways originating in the rat nucleus accumbens
TLDR
The present data indicate that the neurotensin immunoreactivity‐rich ventromedial district of ventral pallidum receives its accumbal input almost exclusively from the shell district of the nucleus accumbens, which is a uniquely specialized part of the basal ganglia. Expand
Pharmacological characterization of dopamine systems in the nucleus accumbens core and shell
TLDR
There are significant differences between the nucleus accumbens core and nucleus Accumbens shell in basal dopamine metabolism, and this work indicates that the core and shell dopamine innervations can be distinguished on the basis of response to both pharmacological and environmental challenges. Expand
Organization of the projections from the subiculum to the ventral striatum in the rat. A study using anterograde transport of Phaseolus vulgaris leucoagglutinin
TLDR
It appears that not only the entire nucleus accumbens, part of the so-called ventral striatum, receives fibres from the subiculum, but that the hippocampal projection area in the striatum includes also the most medial, ventral, rostral and caudal parts of the caudate-putamen complex. Expand
Cytoarchitectonic heterogeneity of the primate neostriatum: Subdivision into island and matrix cellular compartments
TLDR
According to present observations the neostriatum in primates should be viewed as a cytoarchitectonically heterogeneous structure composed of at least two distinct cellular compartments with specific connectivity related to the histochemical and functional diversity of the nestriatum. Expand
...
1
2
3
4
5
...