Morphological correlates of corticosteroid-induced changes in prefrontal cortex-dependent behaviors.

@article{Cerqueira2005MorphologicalCO,
  title={Morphological correlates of corticosteroid-induced changes in prefrontal cortex-dependent behaviors.},
  author={Jo{\~a}o Jos{\'e} Cerqueira and Jos{\'e} Miguel P{\^e}go and Ricardo Taipa and Jo{\~a}o Miguel Bessa and Osborne F X Almeida and Nuno Sousa},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2005},
  volume={25 34},
  pages={7792-800}
}
Imbalances in the corticosteroid milieu have been implicated in several neuropsychiatric disorders, including depression and schizophrenia. Prefrontal cortex (PFC) dysfunction is also a hallmark of these conditions, causing impairments in executive functions such as behavioral flexibility and working memory. Recent studies have suggested that the PFC might be influenced by corticosteroids released during stress. To test this possibility, we assessed spatial working memory and behavioral… CONTINUE READING
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