Morphological basis for the spectrum of clinical deficits in spinocerebellar ataxia 17 (SCA17).

  title={Morphological basis for the spectrum of clinical deficits in spinocerebellar ataxia 17 (SCA17).},
  author={Kathrin Lasek and Rebekka Lencer and Christian Gaser and Johannes M. Hagenah and Uwe Walter and Alexander Wolters and Norman Kock and Susanne Steinlechner and Matthias Nagel and Christine Zuehlke and M Nitschke and Katja Brockmann and Christine A. Klein and Arndt Rolfs and F. Binkofski},
  journal={Brain : a journal of neurology},
  volume={129 Pt 9},
Spinocerebellar ataxia 17 (SCA17) is a rare genetic disorder characterized by cerebellar, extrapyramidal, pyramidal as well as psychiatric signs. The pathoanatomical basis of this disorder is still not well known. A total of 12 patients and 12 age- and sex-matched controls were examined by in vivo MRI voxel-based morphometry (VBM). Besides general patterns of disease-related brain atrophy, characteristic syndrome-related morphological changes in SCA17 patients were studied. In comparison with… CONTINUE READING


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Unified Parkinson’s Disease Rating Scale. Recent developments in Parkinson’s disease

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