Morphological aspects in phase-contrast and transmission electron microscopy of senescent cultures of bovine aortic endothelial cells.

@article{Weber1984MorphologicalAI,
  title={Morphological aspects in phase-contrast and transmission electron microscopy of senescent cultures of bovine aortic endothelial cells.},
  author={Elisabetta Weber and Rosella Vatti and Gilberto Berti},
  journal={Bollettino della Societa italiana di biologia sperimentale},
  year={1984},
  volume={60 9},
  pages={1643-9}
}
Some cultures of bovine aortic endothelial cells underwent an early senescence process, which may have been favoured by a special differential attachment trypsinization procedure. In order to better characterize this phenomenon, the cultures were observed at phase-contrast and electron microscopy at various passages. In phase-contrast microscopy, senescent cells were always larger than "younger" cells, and giant cells were very frequent. A great heterogeneity both of shape and size was present… CONTINUE READING