Morphological and molecular characteristics of "difficult" asthma.

  title={Morphological and molecular characteristics of "difficult" asthma.},
  author={Polina A Selivanova and Evgeny S Kulikov and Olga V Kozina and Elena A Gereng and Maxim B Freidin and Ludmila M. Ogorodova},
  journal={The Journal of asthma : official journal of the Association for the Care of Asthma},
  volume={47 3},
BACKGROUND There are several clinical variants of severe difficult-to-treat asthma: asthma with persistent airflow limitation, brittle asthma, and fatal asthma; but the differences between the pathogenetic mechanisms underlying the disease heterogeneity are unknown. OBJECTIVES The aim was to evaluate the morphological and molecular characteristics of brittle asthma type I and asthma with persistent airflow limitation compared to mild-to-moderate asthma, by the analysis of the cellular… CONTINUE READING
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Particular qualities of apoptosis of eosiniphils in patients with severe treatment-resistant asthma

  • LY Nicitina, FI Petrovsky, II Ivanchuk, AE. Sazonov
  • Bull Siberian Med
  • 2005
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