Morphological and functional preservation of the outer hair cells from noise trauma by sound conditioning

  title={Morphological and functional preservation of the outer hair cells from noise trauma by sound conditioning},
  author={Barbara Canlon and Anette Fransson},
  journal={Hearing Research},
Reducing noise damage by using a mid‐frequency sound conditioning stimulus
It is demonstrated that mid-frequency sound conditioning protects against noise trauma and that the protective effect is maintained for at least 1 week.
Protection against Noise Trauma by Sound Conditioning
It has been shown that after exposure to a traumatic stimulus, sound conditioning protects the outer hair cell morphology, as well as physiology, compared to an unconditioned group exposed only to the traumatic stimulus.
Effect of sound conditioning on click auditory brainstem response threshold shifts in guinea pigs
Electrophysiological data of this study showed that sound conditioning has a protective effect against subsequent intensive noise exposure, and the frequency of conditioning does not have significant effect on ABR threshold shifts when click stimulus is used.
Conditioning-induced protection from impulse noise in female and male chinchillas.
The results show that significant protection from impulse noise can be achieved with a 5-day conditioning regimen, and that there are consistent differences between female and male chinchillas in the response of the cochlea to impulse noise.
Long-term sound conditioning enhances cochlear sensitivity.
Comparison with the frequency range and magnitude of conditioning-related protection suggests that the protection cannot be completely explained by amplification of the OC reflex and the known protective effects of OC feedback, and suggests that sound conditioning leads to changes in the physiology of the outer hair cells themselves, the peripheral targets of theOC reflex.
Protection against Acoustic Trauma by Forward and Backward Sound Conditioning
Findings are important for understanding how the auditory system can be modulated by acoustic stimulation and highlights the importance of the acoustic environment during the recovery process of the auditorysystem.


Effect of periodic rest on hearing loss and cochlear damage following exposure to noise.
Behavioral and anatomical data indicated that these intermittent exposures to an octave band of noise produced less temporary and permanent hearing loss and less cochlear damage than continuous exposures of equal energy.
Measures of auditory brain-stem responses, distortion product otoacoustic emissions, hair cell loss, and forward masked tuning curves in the waltzing guinea pig.
Measures of the auditory brain-stem response (ABR), distortion product otoacoustic emission (2f1-f2), hair cell loss, and forward masked tuning curves were obtained from waltzing guinea pigs and their age-matched controls and showed progressive decreases in sensitivity with increasing age.
Effect of temperature on cochlear responses during and after exposure to noise.
  • D. Drescher
  • Physics
    The Journal of the Acoustical Society of America
  • 1976
The studies indicate that noise‐induced reduction of CM may be linked to processes of energy metabolism and/or may involve temperature‐dependent structural changes that do not affect normal cochlear response.
Hypothermia protects the cochlea from noise damage