Morphological and functional effects of Na2EDTA on the outflow routes for aqueous humor in monkeys.

@article{Hamanaka1987MorphologicalAF,
  title={Morphological and functional effects of Na2EDTA on the outflow routes for aqueous humor in monkeys.},
  author={Toshihiko Hamanaka and Anders Bill},
  journal={Experimental eye research},
  year={1987},
  volume={44 2},
  pages={171-90}
}
The chelating agent Na2EDTA was perfused through the anterior chambers of monkeys eyes in an attempt to find a concentration that would cause a rise in outflow facility without harming the cornea or anterior uvea. Na2EDTA (0.5 mM) proved effective in increasing the facility within 60 min. There were marked effects on the tissue at the iridocorneal chamber angle with loss of cell processes from the trabecular cells, ballooning of the juxtacanalicular region and the inner wall of Schlemm's canal… CONTINUE READING