Morphological and functional differentiation in BE(2)-M17 human neuroblastoma cells by treatment with Trans-retinoic acid

@inproceedings{Andres2012MorphologicalAF,
  title={Morphological and functional differentiation in BE(2)-M17 human neuroblastoma cells by treatment with Trans-retinoic acid},
  author={Devon K Andres and Brian M. Keyser and John P. Petrali and Betty J. Benton and Kyle S. Hubbard and Patrick Michael McNutt and Radharaman Ray},
  booktitle={BMC Neuroscience},
  year={2012}
}
Immortalized neuronal cell lines can be induced to differentiate into more mature neurons by adding specific compounds or growth factors to the culture medium. This property makes neuronal cell lines attractive as in vitro cell models to study neuronal functions and neurotoxicity. The clonal human neuroblastoma BE(2)-M17 cell line is known to differentiate into a more prominent neuronal cell type by treatment with trans-retinoic acid. However, there is a lack of information on the morphological… CONTINUE READING
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