Morphological and chemical studies of pathological human and mice brain at the subcellular level: correlation between light, electron, and nanosims microscopies.

@article{Quintana2007MorphologicalAC,
  title={Morphological and chemical studies of pathological human and mice brain at the subcellular level: correlation between light, electron, and nanosims microscopies.},
  author={C Quintana and Ting-di Wu and Benoit Delatour and Marc Dhenain and Jean Luc Guerquin-Kern and Alain Croisy},
  journal={Microscopy research and technique},
  year={2007},
  volume={70 4},
  pages={281-95}
}
Neurodegenerative diseases induce morphological and chemical alterations in well-characterized regions of the brain. Understanding their pathological processes requires the use of methods that assess both morphological and chemical alterations in the tissues. In the past, microprobe approaches such as scanning electron microscopy combined with an X-ray spectrometer, Proton induced X-ray emission, secondary ion mass spectrometry (SIMS), and laser microprobe mass analysis have been used for the… CONTINUE READING

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