Morphological and biomolecular characteristics of subcentimetric invasive breast carcinomas in Sicily: A multicentre retrospective study in relation to trastuzumab treatment.

@article{Ieni2012MorphologicalAB,
  title={Morphological and biomolecular characteristics of subcentimetric invasive breast carcinomas in Sicily: A multicentre retrospective study in relation to trastuzumab treatment.},
  author={Antonio Ieni and Giuseppe Giuffr{\'e} and Salvatore Lanzafame and Giuseppe Nuciforo and M Curduman and Liliana Villari and Elena Roz and Giovanna Certo and Daniela Cabibi and Enrica Salomone and Agata Labate and Domenico Messina and Vito Franco and Vincenzo Adamo and Giovanni Tuccari},
  journal={Oncology letters},
  year={2012},
  volume={3 1},
  pages={141-146}
}
Little information from clinical trials is available regarding the efficacy of trastuzumab treatment in subcentimetric breast carcinomas (BCs). The aim of this study was to verify the existence of correlations between HER2 and hormone receptor status, Ki67 values, grade, histotype and node involvement in a cohort of pT1a,b BCs from an area not widely covered by screening campaigns. A total of 410 pT1a,b BC formalin-fixed paraffin-embedded samples collected from eight Sicilian Anatomo… CONTINUE READING

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