Morphological and biochemical features of obesity are associated with mineralization genes’ polymorphisms

@article{Korostishevsky2010MorphologicalAB,
  title={Morphological and biochemical features of obesity are associated with mineralization genes’ polymorphisms},
  author={M. Korostishevsky and Z. Cohen and I. Malkin and S. Ermakov and O. Yarenchuk and G. Livshits},
  journal={International Journal of Obesity},
  year={2010},
  volume={34},
  pages={1308-1318}
}
Background:Ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1) was recently extensively studied as a candidate gene for obesity phenotypes. As the human homologue of the mouse progressive ankylosis (ANKH) and alkaline phosphatase (ALPL) are known functional partners of ENPP1 in bone mineralization, we hypothesized that these genes may also be jointly involved in determining obesity features.Aim:To examine the effects of the three genes, possible gene–sex and gene–gene interactions on… Expand
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