The morphology, lipid composition, and activity of sphingomyelinase (E.C. 220.127.116.11) and phospholipases A (E.C. 18.104.22.168) and C (E.C. 22.214.171.124) were studied in the urinary cells from four normal subjects, four patients receiving gentamicin (G), and four patients receiving cyclosporin-A (CsA). We report that abnormal urinary excretion of proximal tubular cells… (More)
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