Morphological analysis of selective destruction of pancreatic beta-cells by cytotoxic T lymphocytes in NOD mice.

@article{Hayakawa1991MorphologicalAO,
  title={Morphological analysis of selective destruction of pancreatic beta-cells by cytotoxic T lymphocytes in NOD mice.},
  author={Masayuki Hayakawa and Koich Yokono and Masao Nagata and N. Hatamori and Wataru Ogawa and Akinori Miki and Humio Mizoguti and Shiro Baba},
  journal={Diabetes},
  year={1991},
  volume={40 9},
  pages={1210-7}
}
Interactions of pancreatic islets and islet-associated mononuclear cells (IAMCs) from the nonobese diabetic (NOD) mouse were morphologically investigated. To obtain IAMCs, pancreatic islets isolated from adult NOD mice were cultured for 7 days with interleukin 2. Noted by light microscopy, interactions between IAMCs and freshly isolated islets from young… CONTINUE READING