Morphological alterations in neurons forming corticocortical projections in the neocortex of aged Patas monkeys.

@article{Page2002MorphologicalAI,
  title={Morphological alterations in neurons forming corticocortical projections in the neocortex of aged Patas monkeys.},
  author={Tanya L Page and Michael C Einstein and Huiling Duan and Yong He and Tony Flores and Daniil Rolshud and Joseph M. Erwin and Susan L. Wearne and John Morrison and Patrick R. Hof},
  journal={Neuroscience letters},
  year={2002},
  volume={317 1},
  pages={37-41}
}
Recent studies indicate that the cognitive processes mediated by the prefrontal cortex, such as working memory, are impaired during normal aging. These disturbances in cortical function may be a consequence of abnormalities in neocortical circuits, even though the numbers of cortical neurons are preserved in normal aging. We performed retrograde tract-tracing of cortical projections connecting the temporal cortex to the prefrontal cortex in combination with dye-filling and three-dimensional… CONTINUE READING

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