Morphologic diversity of malignant neoplasms arising in preexisting spiradenoma, cylindroma, and spiradenocylindroma based on the study of 24 cases, sporadic or occurring in the setting of Brooke-Spiegler syndrome.

@article{Kazakov2009MorphologicDO,
  title={Morphologic diversity of malignant neoplasms arising in preexisting spiradenoma, cylindroma, and spiradenocylindroma based on the study of 24 cases, sporadic or occurring in the setting of Brooke-Spiegler syndrome.},
  author={Dmitry V Kazakov and Bernhard Zelger and Arno R{\"u}tten and Marina Vazmitel and Dominic V. Spagnolo and Denisa Kacerovsk{\'a} and Tom{\'a}{\vs} Vaně{\vc}ek and Petr Grossmann and Radek Sima and W Randall Grayson and Eduardo Calonje and Jan Henrik Koren and Petr Muken{\vs}n{\'a}bl and Du{\vs}an Dani{\vs} and M Igielski Michal},
  journal={The American journal of surgical pathology},
  year={2009},
  volume={33 5},
  pages={
          705-19
        }
}
The authors present a series of 24 malignant neoplasms arising in preexisting benign spiradenoma (20), cylindroma (2), and spiradenocylindroma (2). Nineteen patients (12 females, 7 males; age range, 41 to 92 y) had a solitary neoplasm (size range, 2.2 to 17.5 cm; median 4 cm), whereas the remaining 5 (4 females, 1 male; age range, 66 to 72 y) manifested clinical features of Brooke-Spiegler syndrome (BSS), an autosomal dominantly inherited disease characterized by widespread, small, benign… CONTINUE READING
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