Morphologic changes in the mesolimbic pathway in Parkinson's disease motor subtypes.

@article{Nyberg2015MorphologicCI,
  title={Morphologic changes in the mesolimbic pathway in Parkinson's disease motor subtypes.},
  author={Eric MacKenzie Nyberg and Jody Tanabe and Justin Morris Honce and Theodore D Krmpotich and Erika Shelton and Jessica Louise Hedeman and Brian D. Berman},
  journal={Parkinsonism & related disorders},
  year={2015},
  volume={21 5},
  pages={536-40}
}
BACKGROUND Parkinson's disease (PD) is a common neurodegenerative disorder associated with gray matter atrophy. Cortical atrophy patterns may further help distinguish between PD motor subtypes. Comparable differences in subcortical volumes have not been found. METHODS Twenty-one cognitively intact and treated PD patients, including 12 tremor dominant (TD) subtype, Nine postural instability gait dominant (PIGD) subtype, and 20 matched healthy control subjects underwent 3.0 T high-resolution… CONTINUE READING