Morphologic Correlates of Renal Growth Arrest in Neonatal Partial Ureteral Obstruction

  title={Morphologic Correlates of Renal Growth Arrest in Neonatal Partial Ureteral Obstruction},
  author={Robert L. Chevalier and Benjamin C. Sturgill and Catherine E Jones and Donald L. Kaiser},
  journal={Pediatric Research},
ABSTRACT: To investigate the morphologic correlates of decreased renal blood flow and growth arrest resulting from chronic partial ureteral obstruction in the neonate, guinea pigs were subjected to unilateral ureteral constriction within the first 2 days of life and were studied at 3 and 8 wk of age. Severity of histologic changes in the obstructed and intact contralateral kidney was assessed by light microscopy. Morphometric glomerular measurements were made using a computerized tracing device… CONTINUE READING
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