Morphogenetic plasticity of adult human pancreatic islets of Langerhans

Abstract

The aim of this study was to investigate the phenotypic plasticity of pancreatic islets of Langerhans. Quiescent adult human islets were induced to undergo a phenotypic switch to highly proliferative duct-like structures in a process characterized by a loss of expression of islet-specific hormones and transcription factors as well as a temporally related… (More)
DOI: 10.1038/sj.cdd.4401617

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