Morphogenesis of Plasmodium zoites is uncoupled from tensile strength

  title={Morphogenesis of Plasmodium zoites is uncoupled from tensile strength},
  author={Annie Z. Tremp and Victoria Carter and Sadia Saeed and Johannes T. Dessens},
  booktitle={Molecular microbiology},
A shared feature of the motile stages (zoites) of malaria parasites is a cortical cytoskeletal structure termed subpellicular network (SPN), thought to define and maintain cell shape. Plasmodium alveolins comprise structural components of the SPN, and alveolin gene knockout causes morphological abnormalities that coincide with markedly reduced tensile strength of the affected zoites, indicating the alveolins are prime cell shape determinants. Here, we characterize a novel SPN protein of… CONTINUE READING
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