Morphogenesis, evolution and prognostic significance of lymphatic tissue lesions in HIV infection.

@article{Vago1989MorphogenesisEA,
  title={Morphogenesis, evolution and prognostic significance of lymphatic tissue lesions in HIV infection.},
  author={Luca Vago and M. Antonacci and Silvano Cristina and Carlo Parravicini and Adriano Lazzarin and Leonardo Sacco and Chiara Negri and Caterina Uberti-Foppa and Massimo Musicco and Giulio Costanzi},
  journal={Applied pathology},
  year={1989},
  volume={7 5},
  pages={
          298-309
        }
}
Morphological changes in lymph node biopsies of HIV-infected patients can be classified in four stages, based upon the degree of damage to follicular structures: (1) follicular hyperplasia, (2) follicular lysis, (3) follicular atrophy and (4) follicular and lymphocytic depletion. To define the relative usefulness of morphological, clinical and immunological findings for prognostic purposes, we followed the clinical evolution of 86 biopsied HIV+ patients for a period ranging from 1 to 56 months… CONTINUE READING