Morphine selectively influences macronutrient intake in the rat.

  title={Morphine selectively influences macronutrient intake in the rat.},
  author={Robin Marks-Kaufman and Robin B. Kanarek},
  journal={Pharmacology, biochemistry, and behavior},
  volume={12 3},
Dietary self-selection of the three macronutrients, protein, carbohydrate and fat, was examined in male rats following the administration of three doses of morphine sulphate: 10 mg, 15 mg, and 30 mg/kg body weight. Intakes of all three macronutrients were suppressed in a dose-dependent manner for a two-hour period following morphine administration. Both protein and carbohydrate intakes remained suppressed for a six-hour feeding period after morphine injections. In contrast, animals increased… CONTINUE READING