Morphine modulates proliferation of kidney fibroblasts.

  title={Morphine modulates proliferation of kidney fibroblasts.},
  author={Pravin C. Singhal and Pawan Sharma and Vibha Sanwal and Anil Prasad and Aditi A. Kapasi and Rajiv Ranjan and Nicholas Franki and K. Raghunandan Reddy and Nora E Gibbons},
  journal={Kidney international},
  volume={53 2},
Renal interstitial scarring is an important component of heroin-associated nephropathy. Kidney fibroblasts have been demonstrated to play a role in the development of renal scarring in a variety of renal diseases. We studied the effect of morphine, an active metabolite of heroin, on the proliferation of kidney fibroblasts. Morphine at a concentration of 10… CONTINUE READING