Morphine compared with diamorphine
@article{Robinson1991MorphineCW, title={Morphine compared with diamorphine}, author={S. L. Robinson and David J. Rowbotham and G. Smith}, journal={Anaesthesia}, year={1991}, volume={46} }
The dose requirements and side effects of morphine were compared with those of diamorphine administered by patient‐controlled analgesia in 40 patients following elective total hip replacement. Patients were allocated randomly to receive in a double‐blind manner either morphine or diamorphine for postoperative pain relief. There were no significant differences between the two groups with regard to postoperative sedation, nausea, well‐being, pain relief and requirements for antiemetic drugs. The…
18 Citations
Dose requirements, efficacy and side effects of morphine and pethidine delivered by patient-controlled analgesia after gynaecological surgery.
- MedicineBritish journal of anaesthesia
- 1996
We have compared the dose requirements and side effects of morphine with those of pethidine when administered by patient-controlled analgesia in 40 patients (ASA I-II, 20-65 yr) after elective total…
Hypoxaemia and pain relief after lower abdominal surgery: comparison of extradural and patient-controlled analgesia.
- MedicineBritish journal of anaesthesia
- 1992
Extradural infusion analgesia produced the smallest pain scores from 12 to 24 h after surgery (P < 0.05), and the group using patient-controlled analgesia received more diamorphine and suffered a greater incidence of emetic sequelae.
efficacy . analgesia : assessment of safety and Intranasal diamorphine for paediatric
- Medicine
- 2005
Intranasal diamorphine is an effective, safe, and acceptable method ofanalgesia for children requiring opiates in the A&E department.
Patient-controlled epidural diamorphine for post-operative pain: verbal rating and visual analogue assessments of pain.
- MedicineEuropean journal of anaesthesiology
- 1996
Epidural PCA began when the intraoperative epidural block with bupivacaine wore off enough for the patient to request treatment, and clinically acceptable analgesia was maintained without undue sedation for 48 h, though pain on coughing was less well controlled than pain at rest.
Side Effect Rates of Opioids in Equianalgesic Doses Via Intravenous Patient-Controlled Analgesia: A Systematic Review and Network Meta-analysis.
- MedicineAnesthesia and analgesia
- 2018
The opiate chosen for treatment most likely has little effect on the incidence of pruritus and nausea/vomiting, although considerable differences exist in terms of better and worse opioids in the presented rankings.
Intranasal diamorphine for paediatric analgesia: assessment of safety and efficacy.
- MedicineJournal of accident & emergency medicine
- 1997
Intranasal diamorphine is an effective, safe, and acceptable method of analgesia for children requiring opiates in the A & E department.
Effects of High-Dose Heroin versus Morphine in Intravenous Drug Users: A Randomised Double-Blind Crossover Study
- MedicineJournal of psychoactive drugs
- 2001
It is concluded that as heroin produces fewer side effects it is the preferred highdose maintenance prescription to morphine, and the perceived euphoric effects are limited in both substances.
Intranasal Diamorphine as an Alternative to Intramuscular Morphine
- Medicine, BiologyClinical pharmacokinetics
- 2003
Intranasal diamorphine provided the same overall degree of pain relief as intramuscular morphine, but with a quicker onset of action, and was found to be well tolerated with an acceptable safety profile.
Patient-controlled analgesia.
- MedicineThe Medical letter on drugs and therapeutics
- 1989
Patient-controlled delivery systems deliver drugs at a rate which is controlled by the patient in order to achieve plasma concentrations consistent with acceptable efficacy and minimal side-effects to evaluate alternative methods of providing postoperative analgesia.
Multicentre randomised controlled trial of nasal diamorphine for analgesia in children and teenagers with clinical fractures
- MedicineBMJ : British Medical Journal
- 2001
Nasal diamorphine spray should be the preferred method of pain relief in children and teenagers presenting to emergency departments in acute pain with clinical fractures and should be used in place of intramuscular morphine.
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