Morphine and nigrostriatal function in the rat and mouse: the role of nigral and striatal opiate receptors.

@article{Wood1982MorphineAN,
  title={Morphine and nigrostriatal function in the rat and mouse: the role of nigral and striatal opiate receptors.},
  author={Paul L Wood and Jean W. Richard},
  journal={Neuropharmacology},
  year={1982},
  volume={21 12},
  pages={1305-10}
}
Using local injections of drugs and hemisection experiments, a comparison was made of the actions of morphine on the dopaminergic nigrostriatal system of the rat and mouse. In the rat, morphine appeared to act exclusively at presynaptic opiate receptors on dopaminergic nerve endings in the striatum. Activation of these receptors resulted in enhanced… CONTINUE READING

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