Morphine and ethanol as discriminative stimuli: Absence of antagonism by p-chlorophenylalanine methyl ester, cinanserin, or BC-105

@article{Winter2004MorphineAE,
  title={Morphine and ethanol as discriminative stimuli: Absence of antagonism by p-chlorophenylalanine methyl ester, cinanserin, or BC-105},
  author={J. Winter},
  journal={Psychopharmacology},
  year={2004},
  volume={53},
  pages={159-163}
}
  • J. Winter
  • Published 2004
  • Chemistry, Medicine
  • Psychopharmacology
  • It is well established that the effects of morphine and ethanol can function as discriminative stimuli in the rat. The present investigation sought to determine whether discriminated responding mediated by morphine and ethanol is affected by (a) p-chlorophenylalanine methyl ester (p-CPA) an inhibitor of the synthesis of 5-hydroxytryptamine (5-HT) and (b) antagonists of 5-HT. The blocking agents employed were cinanserin, in ethanol-trained subjects, and BC-105, in morphine-trained subjects. No… CONTINUE READING
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