• DOI:10.1002/MED.20035
Corpus ID: 20887610

Morphine‐6‐glucuronide: Actions and mechanisms

@article{Kilpatrick2005Morphine6glucuronideAA,
  title={Morphine‐6‐glucuronide: Actions and mechanisms},
  author={Gavin Kilpatrick and T. Smith},
  journal={Medicinal Research Reviews},
  year={2005},
  volume={25}
}

Gavin Kilpatrick, T. Smith

Published 2005

Medicine

Medicinal Research Reviews

Morphine‐6‐glucuronide (M6G) appears to show equivalent analgesia to morphine but to have a superior side‐effect profile in terms of reduced liability to induce nausea and vomiting and respiratory depression. The purpose of this review is to examine the evidence behind this statement and to identify the possible reasons that may contribute to the profile of M6G. The vast majority of available data supports the notion that both M6G and morphine mediate their effects by activating the µ‐opioid… CONTINUE READING

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