Morning and evening peaks of activity rely on different clock neurons of the Drosophila brain

@article{Grima2004MorningAE,
  title={Morning and evening peaks of activity rely on different clock neurons of the Drosophila brain},
  author={B. Grima and Elisabeth Ch{\'e}lot and Ruohan Xia and François Rouyer},
  journal={Nature},
  year={2004},
  volume={431},
  pages={869-873}
}
In Drosophila, a ‘clock’ situated in the brain controls circadian rhythms of locomotor activity. This clock relies on several groups of neurons that express the Period (PER) protein, including the ventral lateral neurons (LNvs), which express the Pigment-dispersing factor (PDF) neuropeptide, and the PDF-negative dorsal lateral neurons (LNds). In normal cycles of day and night, adult flies exhibit morning and evening peaks of activity; however, the contribution of the different clock neurons to… CONTINUE READING
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Drosophila cry(b) mutation reveals two circadian clocks that drive locomotor rhythm and have different responsiveness to light

  • T Yoshii
  • J. Insect Physiol
  • 2004

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