Morituri te salutant? Olfactory signal transduction and the role of phosphoinositides

  title={Morituri te salutant? Olfactory signal transduction and the role of phosphoinositides},
  author={Rebecca Elsaesser and Jacques Paysan},
  journal={Journal of Neurocytology},
  • Rebecca Elsaesser, Jacques Paysan
  • Published 2005
  • Biology, Medicine
  • Journal of Neurocytology
  • During the past 150 years, researchers have investigated the cellular, physiological, and molecular mechanisms underlying the sense of smell. Based on these efforts, a conclusive model of olfactory signal transduction in the vertebrate's nose is now available, spanning from G-protein-mediated odorant receptors to ion channels, which are linked by a cyclic adenosine 3',5'-monophosphate-mediated signal transduction cascade. Here we review some historical milestones in the chronology of olfactory… CONTINUE READING
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