Corpus ID: 26800167

Moringa oleifera Lam. leaf extract prevents early liver injury and restores antioxidant status in mice fed with high-fat diet.

@article{Das2012MoringaOL,
  title={Moringa oleifera Lam. leaf extract prevents early liver injury and restores antioxidant status in mice fed with high-fat diet.},
  author={N. Das and Kunal Sikder and Santinath Ghosh and B. Fromenty and S. Dey},
  journal={Indian journal of experimental biology},
  year={2012},
  volume={50 6},
  pages={
          404-12
        }
}
Consumption of high-fat diet (HFD) induces nonalcoholic fatty liver disease (NAFLD) and may lead to multiple complications affecting human health. In the present study, effect of Moringa oleifera leaf extract (MoLE) in alleviating HFD induced liver injury in mice has been reported. Liver histology and serum activity of hepatic marker enzymes i.e. aspartate aminotransferase (AST), alanine aminotransferase (ALT) and alkaline phosphatase (ALP) have been studied. Lipid peroxidation (LPO), ferric… Expand
Moringa oleifera Lam. seed extract prevents fat diet induced oxidative stress in mice and protects liver cell-nuclei from hydroxyl radical mediated damage.
TLDR
Moringa oleifera seed extract was found to be polyphenol rich with potent reducing power, free radicals and hydroxyl radicals scavenging activity and can be used as herbal medication against HFD induced ROS mediated disorders. Expand
Hepatoprotective and antioxidant activity of aerial parts of Moringa oleifera in prevention of non-alcoholic fatty liver disease in Wistar rats
Abstract Non-alcoholic fatty liver disease (NAFLD) has a high incidence in Iran. In this study, identification of three antioxidants including caffeic acid, quercetin and gallic acid in leaf and stemExpand
Amelioration of Hepatic Lipid Peroxidation and Insulin Sensitivity by an Ethanolic Extract of Moringa o leif era in Non-Alcoholic Fatty Liver Disease (NAFLD) in Rats
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Cardiac Ameliorative Effect of Moringa oleifera Leaf Extract in High-Fat Diet-Induced Obesity in Rat Model
TLDR
The treatment with the methanolic extract of Moringa oleifera leaves alleviated abnormalities in the serum biochemical parameters, balanced the antioxidant status, and reestablished the normal histological structure of the heart especially in the case of the higher concentration. Expand
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TLDR
It is concluded that short-term treatment with Moringa oleifera leaf extract and its constituent quercetin prevent HFD-mediated inflammation in mice. Expand
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The main target of this study was to investigate the beneficial effects of Moringa oleifera (MO) (leaves and roots) on nutritional values, protection against oxidative stress and hepato protectiveExpand
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Efficacy of Moringa oleifera Aqueous Extract in Inhibiting Tamoxifen®-Induced Physiological Hepatic Deterioration in Male Albino Rats.
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The molecular mechanism underlying the hepatoprotective potential of Moringa oleifera leaves extract against acetaminophen induced hepatotoxicity in mice
Moringa oleifera (MO) is ubiquitous in nature with high nutritional and medicinal value. Numerous studies have reported its remarkable activity against an array of clinical complications includingExpand
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