More than just a T-box: the role of T-bet as a possible biomarker and therapeutic target in autoimmune diseases.

Abstract

T-bet was initially described as a T-box transcription factor with an essential role in orchestrating Th1 cell differentiation. Subsequently, it was determined that T-bet controls the expression of numerous cytokines and their receptors, adhesion molecules and chemokine receptors, and therefore determines the differentiation and development status of many… (More)
DOI: 10.2217/imt.10.111

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Cite this paper

@article{Ji2011MoreTJ, title={More than just a T-box: the role of T-bet as a possible biomarker and therapeutic target in autoimmune diseases.}, author={Niannian Ji and Rebecca A Sosa and Thomas G. Forsthuber}, journal={Immunotherapy}, year={2011}, volume={3 3}, pages={435-41} }