More severe clinical course of cardiovascular dysfunction in intensive care unit patients with the 894TT eNOS genotype.

Abstract

The endothelial nitric oxide synthase (eNOS) plays an important homeostatic role in the cardiovascular system (CVS) by maintaining appropriate blood pressure through production of nitric oxide. The 894TT genotype of 894G>T (Glu298Asp, rs1799983), a polymorphic variant of eNOS, has been associated with several vascular diseases. On the basis of this strong… (More)
DOI: 10.4238/2013.February.27.5

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