More on partitioning and inactivation of AIDS virus in immune globulin preparations.

  title={More on partitioning and inactivation of AIDS virus in immune globulin preparations.},
  author={T. Zuck and M. S. Preston and D. Tankersley and M. Wells and A. Wittek and J. Epstein and S. Daniel and M. Phelan and G. Quinnan},
  journal={The New England journal of medicine},
  volume={314 22},
Prince et al. (Feb. 6 issue) recently expressed concern that human T-cell lymphotropic virus Type III (HTLV-III) could be transmitted by intravenous immune globulin preparations. They suggested that conditions used to make intermediate Cohn-Oncley fractions did not inactivate spiked HTLV-III; however they did not study partitioning of HTLV-III into the various fractions. We recently reported the results of such studies. HTLV-III was spiked into the various Cohn-Oncley fractions and its… Expand
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