More harm than good: antiseizure prophylaxis after traumatic brain injury does not decrease seizure rates but may inhibit functional recovery.

@article{Bhullar2014MoreHT,
  title={More harm than good: antiseizure prophylaxis after traumatic brain injury does not decrease seizure rates but may inhibit functional recovery.},
  author={Indermeet Singh Bhullar and Donald Johnson and Julia P Paul and Andrew James Kerwin and Joseph J. Tepas and Eric R. Frykberg},
  journal={The journal of trauma and acute care surgery},
  year={2014},
  volume={76 1},
  pages={54-60; discussion 60-1}
}
BACKGROUND The purposes of this study were to examine the current Brain Trauma Foundation recommendation for antiseizure prophylaxis with phenytoin during the first 7 days after traumatic brain injury (TBI) in preventing seizures and to determine if this medication affects functional recovery at discharge. METHODS The records of adult (age ≥ 18 years) patients with blunt severe TBI who remained in the hospital at least 7 days after injury were retrospectively reviewed from January 2008 to… CONTINUE READING
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