More and More Coronaviruses: Human Coronavirus HKU1

  title={More and More Coronaviruses: Human Coronavirus HKU1},
  author={Patrick C. Y. Woo and Susanna K. P. Lau and Cyril Chik-Yan Yip and Yi Huang and Kwok - Yung Yuen},
After human coronaviruses OC43, 229E and NL63, human coronavirus HKU1 (HCoV-HKU1) is the fourth human coronavirus discovered. HCoV-HKU1 is a group 2a coronavirus that is still not cultivable. The G + C contents of HCoV-HKU1 genomes are 32%, the lowest among all known coronaviruses with complete genome sequences available. Among all coronaviruses, HCoV-HKU1 shows the most extreme codon usage bias, attributed most importantly to severe cytosine deamination. All HCoV-HKU1 genomes contain unique… CONTINUE READING


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